0435. Pressure-support ventilation compared to pressure-controlled ventilation in experimental emphysema
نویسندگان
چکیده
Introduction Emphysema is characterized by irreversible enlargement of the airspaces distal to the terminal bronchiole, accompanied by destruction of their walls, and impairment of cardiac function. Acute exacerbation of emphysema leads to increased morbidity, mortality and, in some cases, requirement of invasive mechanical ventilation (MV). So far, no study has compared the impact of pressure-controlled ventilation (PCV) and pressure-support ventilation (PSV) on lung mechanics and histology as well as cardiac function in experimental emphysema.
منابع مشابه
Pressure-support improves lung protection and reduces cardiovascular dysfunction compared to pressure-controlled ventilation in experimental emphysema
Introduction Acute exacerbations of pulmonary emphysema lead to increased morbidity, mortality and, in some cases, requirement of invasive mechanical ventilation (MV) [1]. So far, no study has compared the biological impact of pressurecontrolled ventilation (PCV) versus pressure-support ventilation (PSV) in experimental emphysema. Our aims were to develop an elastase-induced emphysema model in ...
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